Protein-protein interactions, commonly known as PPIs, are of utmost importance in various biological processes, including but not limited to signal transduction, gene expression, and metabolic pathways. The complexity and sheer significance of PPIs require us to comprehend them in their entirety to unravel the mechanisms underlying these processes and generate innovative drugs for treating diseases….

Multimeric protein complexes are essential components of many cellular processes. These complexes consist of multiple proteins that work together to perform specific functions. To better understand these complexes, researchers use various techniques to identify and characterize the individual proteins that make up these complexes. One powerful tool for studying protein complexes is tandem affinity purification-mass spectrometry…